RAID1 for homeserver, ZFS, BTRFS or ext4 ?

Hi, everybody,
I own a Terramaster F4-424 Max with following storages installed:
2x 1TB M.2 NVME SSDs
4x 3,5" HDDs
1x 32GB NonECC RAM

My plan is to use the 2 NVME SSDs as a RAID1 for the OS and a couple of VMs. One VM shall be configured for OMV using the 4 HDDs via PASSTHROUGH.

My question is, what filesystem would be suitable for my scenario?

- ZFS: I tried to install a ZFS RAID1, but for some reason the system doesn't boot.
- BTRFS: I installed the system on BTRFS RAID1, this works...

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